Pain delays the onset of sleep, causing sleeplessness as well as frequent or early
morning awakenings, preventing you from getting the deep, restful sleep you need.
That’s why, even if you do get some shut-eye, you may not feel rested.
Each Advil Nighttime Liqui-Gel contains 200 mg of ibuprofen and 25 mg of diphenhydramine
hydrochloride, a gentle sleep enhancer. The ibuprofen relieves pain over several
hours; while the diphenhydramine helps you get a full night’s sleep. The combination
of these ingredients reduces your pain, shortens the time it takes to fall asleep
and increases the duration of your sleep. The result: a better night's sleep.
If you can’t sleep because pain is keeping you up, a product that combines a pain
reliever with a sleep enhancer (like Advil Nighttime) can help ease your pain and
increase the duration of your sleep.
Advil Nighttime is the first and only nighttime pain reliever on the Canadian market
that combines the proven pain-relieving power of Advil with an added ingredient
to help you sleep. Whether you have occasional muscle, back, neck or joint pain
or other aches and pains, the ibuprofen in Advil Nighttime can relieve your pain
over several hours. Plus, the gentle sleep enhancer works together with the ibuprofen
to help you get a better night’s sleep.
The two active ingredients of Advil Nighttime, ibuprofen and diphenhydramine, have
a long history of safe and effective use when used as directed. The two ingredients
have been used in Canada for a combined total of more than 70 years — 21 years for
ibuprofen and over 50 years for diphenhydramine.
Adults and children 16-65 years: Take a single dose of 1 or 2 Liqui-Gels at night.
Do not take more than the recommended dosage unless directed by a physician. Do
not exceed 1200 mg of ibuprofen and 300 mg of diphenhydramine (including the 200-400
mg ibuprofen and 25-50 mg diphenhydramine hydrochloride from Advil Nighttime dose)
in 24 hours. Should be taken no sooner than 4-6 hours after the last daytime ibuprofen
or diphenhydramine dose. See
Interactions with this Medication for examples of other
products which contain these ingredients. Do not take for more than 5 consecutive
nights unless directed by a physician.
Do not give to children under 16 unless directed by a physician.
Interactions with this Medication
- Antihistamines, tranquilizers, alcohol or other sedating drugs
- Digoxin
- Diuretics (e.g., for bloating or heart conditions)
- Insulin
- Lithium
- Medications for high blood pressure or depression, including mononamine oxidase
inhibitors (MAOIs)
- Methotrexate
- Oral antidiabetic agents
- Other pain relievers, sleep-aids or cold medicines
Do not take this product at the same time as other medications containing pain relievers
(e.g., ibuprofen, ASA, acetaminophen, naproxen, etc.) or diphenydramine (e.g., allergy
medications, sedating drugs, cough/cold/flu medications, antinausea drugs) etc.
Advil Nighttime is available in package sizes of 10, 20 and 40 Liqui-Gels.
You can purchase Advil Nighttime at your favourite pharmacy, in the pain reliever
aisle.